Early clinical markers of aggressive multiple sclerosis

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Characterising aggressive multiple sclerosis.

OBJECTIVE To explore the occurrence and characteristics of aggressive multiple sclerosis (AMS) in adult-onset multiple sclerosis (MS) patients. METHODS Prospectively collected data (1980-2009) from British Columbia, Canada, were retrospectively analysed. AMS was defined in three different ways (AMS1, 2 and 3): 'AMS1'--confirmed Expanded Disability Status Scale (EDSS) ≥ 6 within 5 years of MS ...

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ژورنال

عنوان ژورنال: Brain

سال: 2020

ISSN: 0006-8950,1460-2156

DOI: 10.1093/brain/awaa081